Pharmaceuticals pills

With our second trial, we wanted to demonstrate a grinding in suspension. We used the second A1 batch and added about 4,5 grams of isopropyl alcohol (for faster evaporation after grinding).

We ground the sample in small steps of only 30 seconds, followed by 15 seconds of programmed pausing time. The speed was set to 650 rpm to have the maximum g-force for grinding.

After two minutes of total grinding time, the sample was comminuted to a thick paste. More of isopropyl alcohol should be added to maintain a motor oil like viscosity for a better grinding result and easier emptying.

It is possible to pack the sample in wet form. We dried the sample inside of our incubator; with only 45 °C. A light reagglomeration was shown. With an optional rotary speed evaporator, the agglomerates should be much softer.

With our second trial, we wanted to demonstrate a grinding in suspension. We used the second A2 sample and added about 4,5 grams of isopropyl alcohol (for faster evaporation) to the sample.

We ground the sample in small steps of only 30 seconds, followed by 15 seconds of programmed pausing time. The speed was set to 650 rpm to have the maximum g-force for grinding.

After two minutes of total grinding time, the sample was comminuted to a thick paste. More of isopropyl alcohol should be added to maintain a motor oil like viscosity. It is possible to pack the sample in wet form. We dried the sample inside of our incubator; with only 45 °C, reagglomeration was shown. With an optional rotary speed evaporator, the agglomerates should be much softer.